Is lack of sleep related to feelings of stress and anxiety?

my friend recently started a job where she's working a lot and at weird hours like 5 am to 1 pm and 8 pm to 10 am..randomly on different days but every single day and she's tired, of course. since starting this job she has been very stressed out and extremely anxious and thinking about things you typically wouldn't think about...i.e. thinking about the steering wheel turning before each turn, etc etc. do you think her sleep deprivation is related to these feelings shes experiencing or no?